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Georges J. F. Köhler

Georges J. F. Köhler

Georges Jean Franz Köhler (April 17, 1946 in Munich – March 1, 1995 in Freiburg im Breisgau) was a German biologist.

Together with César Milstein and Niels Kaj Jerne, Köhler won the Nobel Prize in Physiology or Medicine in 1984, "for work on the immune system and the production of monoclonal antibodies". Milstein and Köhler's technique for producing monoclonal antibodies laid the foundation for the exploitation of antibodies for diagnostics and therapeutics and many scientific applications.

Georges Jean Franz Köhler
BornApril 17, 1946
Munich
DiedMarch 1, 1995(1995-03-01)(aged 48)
NationalityGerman
Known formonoclonal antibodies
AwardsNobel Prize in Physiology or Medicine in 1984
Scientific career
InstitutionsMax Planck Institute of Immunobiology
Doctoral advisorFritz Melchers

Career

In April 1974 Köhler took up a post-doctoral research fellowship at the Laboratory of Molecular Biology in Cambridge, UK where he began working with César Milstein to develop a laboratory tool that could help them investigate the mechanism that underlies the diversity of antibodies. It was during this work that they devised their hybridoma technique for the production of antibodies. Köhler continued his collaboration on the technique when he returned to Basel Institute of Immunology in April 1974.[1] Köhler remained at the Basel Institute for another nine years, during which time he continued investigating antibody diversity and in the early 1980s began working on the development of transgenic mice as a tool to understand the mechanism that underlies self-tolerance. In 1986 Köhler became director of the Max Planck Institute of Immunobiology where he worked until his death in 1995.[2] [3]

See also

University of Freiburg Faculty of Biology

References

[1]
Citation Linkwww.whatisbiotechnology.orgThe Story of César Milstein and Monoclonal Antibodies.
Sep 26, 2019, 9:06 AM
[2]
Citation Linkwww.whatisbiotechnology.orghttp://www.whatisbiotechnology.org/people/kohler
Sep 26, 2019, 9:06 AM
[3]
Citation Linkopenlibrary.orgK. Eichmann, Köhler's Invention (Birkhäuser Verlag, Basel, 2005) University of Freiburg Faculty of Biology
Sep 26, 2019, 9:06 AM
[4]
Citation Linkui.adsabs.harvard.edu1975Natur.256..495K
Sep 26, 2019, 9:06 AM
[5]
Citation Link//doi.org/10.1038%2F256495a010.1038/256495a0
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Citation Link//www.ncbi.nlm.nih.gov/pubmed/11721911172191
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Citation Link//doi.org/10.1007%2Fs11224-006-9042-010.1007/s11224-006-9042-0
Sep 26, 2019, 9:06 AM
[8]
Citation Linkui.adsabs.harvard.edu1995Natur.374..498M
Sep 26, 2019, 9:06 AM
[9]
Citation Link//doi.org/10.1038%2F374498a010.1038/374498a0
Sep 26, 2019, 9:06 AM
[10]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/77003727700372
Sep 26, 2019, 9:06 AM
[11]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/88469708846970
Sep 26, 2019, 9:06 AM
[12]
Citation Linkwww.nobel.sehttp://www.nobel.se/medicine/laureates/1984/
Sep 26, 2019, 9:06 AM
[13]
Citation Linkwww.nobelprize.orghttps://www.nobelprize.org/nobel_prizes/medicine/laureates/1984/kohler.html
Sep 26, 2019, 9:06 AM
[14]
Citation Linkwww.whatisbiotechnology.orgThe Story of César Milstein and Monoclonal Antibodies
Sep 26, 2019, 9:06 AM
[15]
Citation Linkwww.whatisbiotechnology.orghttp://www.whatisbiotechnology.org/people/kohler
Sep 26, 2019, 9:06 AM
[16]
Citation Linkui.adsabs.harvard.edu1975Natur.256..495K
Sep 26, 2019, 9:06 AM
[17]
Citation Linkdoi.org10.1038/256495a0
Sep 26, 2019, 9:06 AM
[18]
Citation Linkwww.ncbi.nlm.nih.gov1172191
Sep 26, 2019, 9:06 AM
[19]
Citation Linkdoi.org10.1007/s11224-006-9042-0
Sep 26, 2019, 9:06 AM
[20]
Citation Linkui.adsabs.harvard.edu1995Natur.374..498M
Sep 26, 2019, 9:06 AM