During her music career, she was briefly a member of the R&B girl group OMG Girlz (later known as OMG). She departed from the group following the release of their first single, "Ain't Nobody," to pursue a solo career.
Around age 10, Reginae started to appear on her mother's reality television show Tiny and Toya. Her mother, Toya Carter, and Tiny Harris (T.I.'s wife) starred in the reality show starting in 2009.
Carter was also a cast member of Growing Up Hip Hop: Atlanta.