Blackwell is originally from Allen, Texas. She first appeared on social media in 2013 when she was 12-year-old and started to gain traction on Vine from her short comedy videos. Before Vine shut down, she had amassed 500,000 followers and more than half a billion loops.
Quenlin has a YouTube channel where she uploads videos focusing on beauty, health, and comedy. Her most popular video is her "Top 100 Vines." One of Blackwell's most viral pieces of content was the Twitter video titled "me hyping myself up every time I see my reflection." The video was tweeted on June 8th, 2017, and as of August 2017 had over 60,000 retweets and 107,000 likes. On May 1st, 2017, Quenlin was featured in Teen Vogue after she made a spoof video of the Met Gala on Twitter.
Quenlin plans to move out of her hometown after she graduates from high school and move to a big city. She describes her fashion as cheap and cute and promotes being stylish on a budget. Quenlin has admitted she has depression and plans to make a video about her experiences in the future.