Early in his career, Dermody was the Director of Research and Development at KnoahSoft.  He was the Co-Founder of Symbiont.io, which he later resigned from for health-related reasons.  In 2013, he was the co-founder and Lead Developer of Counterparty which utilized the Bitcoin blockchain for earl versions of smart contracts.  In addition, he was the Co-Founder of CtiPath which specializes in bespoke monitoring and managed services for enterprise application stacks.  Since December 2017, Dermody has been the Principal of Stoic Capital , an asset management company that focuses on cryptocurrencies.