She had her first acting role at age 19 in an episode of Strong Medicine. Haqq became a part of the show Keeping Up with the Kardashians when her best friend Khloé Kardashian requested her to make an appearance on the show. She played a role in the 2005 movie Sky High. She also had a small role in ATL in 2006. She acted alongside Azura Skye in the 2008 fantasy drama 20 Years After. 
Malika Haqq pictured on Instagram with her son
Malika and rapper O.T. Genasis welcomed their first child Ace Flores together on March 14, 2020. To announce the milestone moment, she shared a photo of her son’s tiny hand sitting inside her and O.T’s palms. Haqq shared the first video of her newborn son on her Instagram feed on May 7. "Can you say ‘Good morning,’ Ace?" she asked her baby in the clip as he cooed. "That was such a good job! Good job, baby. Say ‘I love you.'"