Kesem started his career in 2008 as a System Administrator at Optibase. In 2010-2011 he served as a Paralegal at Eddie Lazar Advocates LLC. In 2014 he became a Consultant, Summer Associate at Deloitte Canada and worked there up to 2016. Kesem is a Co-founder at AION and nuco. In addition, he has a position of a CEO at Bicameral Ventures.
In 2011 Kesem received a Bachelor of Laws and Bachelor of Business from IDC Herzliya. He also holds a Bachelor of Laws from University of Hong Kong and Master of Business Administration from Rotman School of Management.