Arlene Nickell was a resident of Flatgap, Kentucky.

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She was married to James Nickell.

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On February 10, 2018, Joseph Nickell killed his parents, his girlfriend Lindsey Vanhoose, and her mother Patricia Vanhoose in a shooting spree before committing suicide.

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Nickell's parents, James and Arlene Nickell, were gunned down at a residence in the McKenzie Branch area of Flatgap, Kentucky, and Lindsey along with her mother, Patricia, later were fatally shot at an apartment in Paintsville.

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