Nifoxipam
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Nifoxipam
Nifoxipam
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Formula | C15H10FN3O4 |
Molar mass | 315.256 g/mol g·mol−1 |
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Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to lormetazepam and flunitrazepam in mice.[1]
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Legal status | |
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Legal status |
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Identifiers | |
IUPAC name
| |
CAS Number |
|
PubChemCID |
|
ChemSpider |
|
UNII |
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Chemical and physical data | |
Formula | C15H10FN3O4 |
Molar mass | 315.256 g/mol g·mol−1 |
3D model (JSmol) |
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InChI
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See also
List of benzodiazepine designer drugs
Nitrazolam
Nitemazepam
Phenazepam
References
[1]
Citation Linkwww.google.comKlaus Posselt, Hans Heinrich Prof. Med. Wagener, Klaus Gruber (16 October 1985). "Patent EP 0158267 A2 - Pharmaceutical composition containing 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-7-nitro- or 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one and process for their preparation". Retrieved 3 August 2015.CS1 maint: multiple names: authors list (link)
Sep 26, 2019, 3:08 AM
[3]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/11259331Tansel Kilicarslan; Robert L. Haining; Allan E. Rettie; Usanda Busto; Rachel F. Tyndale; Edward M. Sellers (April 2001). "Flunitrazepam Metabolism by Cytochrome P450s 2C19 and 3A4". Drug Metabolism and Disposition. 29 (4): 460–465. PMID 11259331.
Sep 26, 2019, 3:08 AM
[4]
Citation Linkportal.issn.orgMoosmann, Bjoern; King, Leslie A.; Auwärter, Volker (June 2015). "Designer benzodiazepines: A new challenge". World Psychiatry. 14 (2): 248. doi:10.1002/wps.20236. ISSN 1723-8617. PMC 4471986. PMID 26043347.
Sep 26, 2019, 3:08 AM
[5]
Citation Linkwww.kfx.org.ukKevin Flemen (August 2015). "Drug Facts - Newer Unregulated Drugs" (PDF). KFx. Retrieved 15 August 2015.
Sep 26, 2019, 3:08 AM
[7]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/27071765Markus R. Meyer; Madeleine Pettersson Bergstrand; Anders Helander; Olof Beck (May 2016). "Identification of main human urinary metabolites of the designer nitrobenzodiazepines clonazolam, meclonazepam, and nifoxipam by nano-liquid chromatography-high-resolution mass spectrometry for drug testing purposes". Analytical and Bioanalytical Chemistry. 408 (13): 3571–3591. doi:10.1007/s00216-016-9439-6. PMID 27071765.
Sep 26, 2019, 3:08 AM
[8]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/27366870Madeleine Pettersson Bergstrand; Anders Helander; Therese Hansson; Olof Beck (2016). "Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays". Drug Testing and Analysis. 9 (4): 640–645. doi:10.1002/dta.2003. PMID 27366870.
Sep 26, 2019, 3:08 AM
[9]
Citation Linkportal.issn.orgKatselou, Maria; Papoutsis, Ioannis; Nikolaou, Panagiota; Spiliopoulou, Chara; Athanaselis, Sotiris (2016). "Metabolites replace the parent drug in the drug arena. The cases of fonazepam and nifoxipam". Forensic Toxicology. 35 (1): 1–10. doi:10.1007/s11419-016-0338-5. ISSN 1860-8973. PMC 5214877. PMID 28127407.
Sep 26, 2019, 3:08 AM
[20]
Citation Linkwww.google.com"Patent EP 0158267 A2 - Pharmaceutical composition containing 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-7-nitro- or 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one and process for their preparation"
Sep 26, 2019, 3:08 AM