The Marciano Art Foundation (formally named the Maurice and Paul Marciano Art Foundation ) is a non-profit arts foundation located on Wilshire Boulevard in the Mid-Wilshire neighborhood of Los Angeles, California. It was established by the co-founders of Guess, Maurice Marciano and Paul Marciano. The Marcianos opened the museum on May 25, 2017  as an exhibition space to display their 1,500-piece collection of contemporary art. 
Following a recommendation by artist Alex Israel in 2013,  the Marciano Art Foundation paid $8 million to buy the former Scottish Rite Masonic Temple on Wilshire Boulevard.  Then the building has been transformed by contemporary architect Kulapat Yantrasast of Why Architecture and Design into an exhibition space.  With 110,000 square feet over four floors, it is as large as the Museum of Contemporary Art, Los Angeles and The Broad.   A 5,000-square-foot sculpture garden by the entrance will feature works by Oscar Tuazon, Danh Vō and Thomas Houseago, among others. 
In order to avoid any conflicts of interest with Maurice Marciano's subsequent co-chairmanship of MOCA, the project was temporarily put on hold.  The museum’s inaugural show, Unpacking: The Marciano Art Foundation , will be organized by guest curator Philipp Kaiser.
About 90 percent of the Marciano Art Foundation’s collection has been amassed since 2010. Today, the foundation owns works by Yael Bartana, Wade Guyton, Glenn Ligon, Alex Israel, Albert Oehlen, Mai-Thu Perret, Seth Price, Sterling Ruby, Paul Sietsema, Rudolf Stingel, Kaari Upson, Adrián Villar Rojas, and Christopher Wool, among others.