Science and technology

• Maximum length sequence, a type of pseudorandom binary sequence

• Medical laboratory scientist, a healthcare professional

• Microphthalmia with linear skin defects (MLS) syndrome, a disorder

• Microwave landing system, an aircraft landing-system

• Microwave Limb Sounder, scientific experiments for measuring microwave emission from the limb of Earth's atmosphere

• Moving least squares, a method of reconstructing continuous functions from a set of unorganized point samples, in mathematics and computer graphics.

• Multi-layer steel, a type of automotive head gasket

• Multilayer switch, a computer-networking device

• Multilevel security, for protecting computer data

• Multivariate Least Squares, another name for Regression analysis#General linear model in statistics

Academic degrees

• Master of Legal Studies, similar to Master of Studies in Law

• Master of Liberal Studies, similar to Master of Arts in Liberal Studies

• Master of Library Science, similar to Master of Library and Information Science

Companies

• Maritime Launch Services, U.S. owned spacelaunch company based in Canada using Ukrainian rockets

• MLS (Making Life Simple) S.A., a software engineering company

Schools

• Martin-Luther-Schule, a school in Hesse, Germany

• Michigan Lutheran Seminary, a preparatory high-school in Saginaw, Michigan, US

Other uses

• Multiple listing service, electronic real-estate database in North America

• Mozilla Location Service, an open, crowdsourced geolocation service based on publicly observable cell sites (and their cell IDs) and Wi-Fi access points.