Luis María Drago (May 6, 1859 (1859-05-06) - June 9, 1921 (1921-06-09)) was an Argentine politician.

Born into a distinguished Argentine family in Buenos Aires, Drago began his career as a newspaper editor. Later, he served as a minister of foreign affairs (1902). At that time, when the UK, Germany, and Italy were seeking to collect the public debt of Venezuela by force, he wrote to the Argentine minister in Washington setting forth his doctrine, commonly known as the Drago Doctrine.