Prisma Health Upstate, formerly Greenville Health System (GHS), is a private not-for-profit entity involved in clinical care, education and research. It is part of a health company led by the Strategic Coordinating Organization. The Strategic Coordinating Organization provides strategic direction and corporate services to its affiliates, including GHS. Greenville Health System became Prisma Health in early 2019 after merging with Palmetto Health in Columbia, SC.

GHS first opened its doors as City Hospital back in 1912. Over the last 100 years, the organization has become the state's largest not-for-profit healthcare system.

GHS’ commitment to medical education has also advanced over the years, most notably with the addition of the University of South Carolina School of Medicine Greenville (2012) and the Clemson University School of Nursing (fall of 2018) on GHS’ Greenville Memorial Medical Campus.

Greenville Health System is a not-for-profit, patient-centered, teaching and research institution in South Carolina.

The system has 1,756 licensed beds, 1,985 affiliated and employed medical staff and faculty, and more than 15,000 employees dispersed throughout seven medical campuses and a variety of outpatient and specialty facilities. Its residency and fellowship programs provide training for more than 400 physicians, nursing and allied health students annually.

GHS’ Greenville Memorial Hospital is the state's largest acute care hospital. It contains Greenville's only 24-hour Level 1 trauma center and dedicated chest pain center, children's hospital and ER, pediatric ICU, and highest level neonatal ICU. Its cardiac and women's services are among the largest in South Carolina. Cancer, rehabilitation, mental health, and wellness services—all located on Greenville Memorial Medical Campus—are available as well.

GHS’ Greer Medical Campus is home to Greer Memorial Hospital, an 82-bed facility with a Level III Emergency Trauma Center, ICU, and maternity care. A variety of diagnostic services are available; special services involve cardiac rehabilitation, breast health, and physical and respiratory therapies. The Cottages at Brushy Creek, a 144-bed skilled nursing facility, lies adjacent to the hospital.

GHS’ North Greenville Medical Campus features a 45-bed long-term acute care hospital for adults with complex medical conditions who require an extended stay before returning home. Hospitalists and other staff provide patient-centered services (including dialysis, rehabilitation, and CT scanning). The campus also includes 24-hour emergency care. Outpatient services are available for pediatrics, orthopaedics, and lab and radiology studies.

GHS’ Simpsonville Medical Campus is home to Hillcrest Memorial Hospital, which specializes in short-stay and outpatient surgery. This 43-bed hospital provides 24-hour emergency care; a medical office building is located next to the hospital. Various diagnostic services are available. Specialty programs include bariatric surgery, ENT, sleep disorders, and orthopaedic/sports medicine services.

GHS’ Patewood Medical Campus features Patewood Memorial Hospital which specializes in elective inpatient surgery and maternity care. The campus also focuses on outpatient care, particularly surgery, women's health, and pediatric subspecialties. Lab, radiology, and pharmacy facilities are available, along with home health and orthopaedic/sports medicine offices.

Laurens Memorial Hospital (Laurens, South Carolina)

Oconee Medical Campus (Oconee, South Carolina)

Baptist Easley Hospital (Easley, South Carolina)

Specialty hospitals are located on the Greenville Memorial Medical Campus. These include:

Photographs of the early years of the Greenville Health System can be viewed in the Greenville County Library System digital collections.^[1]