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Glutamate—putrescine ligase

Glutamate—putrescine ligase

In enzymology, a glutamate-putrescine ligase (EC 6.3.1.11 [17] ) is an enzyme that catalyzes the chemical reaction

ATP + L-glutamate + putrescineADP + phosphate + gamma-L-glutamylputrescine

The 3 substrates of this enzyme are ATP, L-glutamate, and putrescine, whereas its 3 products are ADP, phosphate, and gamma-L-glutamylputrescine.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-glutamate:putrescine ligase (ADP-forming). Other names in common use include gamma-glutamylputrescine synthetase, and YcjK. This enzyme participates in urea cycle and metabolism of amino groups.

Glutamate-putrescine ligase
Identifiers
EC number6.3.1.11 [3]
CAS number914090-78-1 [4]
Databases
IntEnzIntEnz view [5]
BRENDABRENDA entry [6]
ExPASyNiceZyme view [7]
KEGGKEGG entry [8]
MetaCycmetabolic pathway [9]
PRIAMprofile [10]
PDB structuresRCSB PDB [11] PDBe [12] PDBsum [13]
Search
PMCarticles [14]
PubMedarticles [15]
NCBIproteins [16]

References

[1]
Citation Link//doi.org/10.1074%2Fjbc.M41111420010.1074/jbc.M411114200
Sep 21, 2019, 4:02 AM
[2]
Citation Link//www.ncbi.nlm.nih.gov/pubmed/1559062415590624
Sep 21, 2019, 4:02 AM
[3]
Citation Linkwww.qmul.ac.uk6.3.1.11
Sep 21, 2019, 4:02 AM
[4]
Citation Linkwww.commonchemistry.org914090-78-1
Sep 21, 2019, 4:02 AM
[5]
Citation Linkwww.ebi.ac.ukIntEnz view
Sep 21, 2019, 4:02 AM
[6]
Citation Linkwww.brenda-enzymes.orgBRENDA entry
Sep 21, 2019, 4:02 AM
[7]
Citation Linkwww.expasy.orgNiceZyme view
Sep 21, 2019, 4:02 AM
[8]
Citation Linkwww.genome.jpKEGG entry
Sep 21, 2019, 4:02 AM
[9]
Citation Linkbiocyc.orgmetabolic pathway
Sep 21, 2019, 4:02 AM
[10]
Citation Linkpriam.prabi.frprofile
Sep 21, 2019, 4:02 AM
[11]
Citation Linkwww.rcsb.orgRCSB PDB
Sep 21, 2019, 4:02 AM
[12]
Citation Linkwww.ebi.ac.ukPDBe
Sep 21, 2019, 4:02 AM
[13]
Citation Linkwww.ebi.ac.ukPDBsum
Sep 21, 2019, 4:02 AM
[14]
Citation Linkwww.ncbi.nlm.nih.govarticles
Sep 21, 2019, 4:02 AM
[15]
Citation Linkwww.ncbi.nlm.nih.govarticles
Sep 21, 2019, 4:02 AM
[16]
Citation Linkwww.ncbi.nlm.nih.govproteins
Sep 21, 2019, 4:02 AM
[17]
Citation Linkenzyme.expasy.org6.3.1.11
Sep 21, 2019, 4:02 AM
[18]
Citation Linkdoi.org10.1074/jbc.M411114200
Sep 21, 2019, 4:02 AM
[19]
Citation Linkwww.ncbi.nlm.nih.gov15590624
Sep 21, 2019, 4:02 AM
[20]
Citation Linken.wikipedia.orgThe original version of this page is from Wikipedia, you can edit the page right here on Everipedia.Text is available under the Creative Commons Attribution-ShareAlike License.Additional terms may apply.See everipedia.org/everipedia-termsfor further details.Images/media credited individually (click the icon for details).
Sep 21, 2019, 4:02 AM