High school career
Perryman attended Coral Gables Senior High School. He recorded 177 tackles, 12 for losses, 9 sacks and 5 interception returns for touchdowns and 9 interceptions as a senior. He was also an area Defensive Player of the Year as a junior, registering 166 solo tackles and had 105 tackles, 9 sacks and 6 interceptions as a sophomore.
Played a true freshman, saw action in all 12 games, earning 8 starts. Finished first among ACC freshmen and second overall on team with 127 tackles (97 solo, 22 assists). Tied for second-highest tackle-for-loss total on team with 6.5. Played in nine games his sophomore season, making nine starts mostly at middle linebacker. He had 64 total tackles (45 solo) and 6.0 tackles-for-loss. Also made Third-team All-ACC.
As a junior in 2013, Perryman was a first-team All- Atlantic Coast Conference (ACC) selection.  He was again an All-ACC selection as a senior in 2014.He was also semi finalist for top linebacker of the year in 2014  />[ 
|Ht||Wt||Arm length||Hand size||40-yd dash||10-yd split||20-yd split||20-ss||3-cone||Vert||Broad||BP|
|5 ft 10.5 in||236 lb||31.9 in||9½ in||4.81u s||32 in||9 ft 5 in||27 reps|
|All values from NFL Combine |
The San Diego Chargers selected Denzel with the 16th pick (48th overall) of the 2nd Round of the 2015 NFL Draft.