Manadaville is originally from New Delhi, India. He attended Vishwas Bharati Public School, Noida and graduated in 2008. He went on to earn a BE in Computer Science Engineering from the Manipal Institute of Technology in 2012 and MS in Biotechnology from Carnegie Mellon University in 2014.
Mandaville was the Chief Technology Officer at Science, Inc. and later became a Special Technical Advisor to the firm. He was the Head of Data Science at Mammoth Media for over a year and a half. In June 2014, he became CEO of SpringRole, which is building a protocol for professional identity. Mandaville serves as an Advisor to Lenny Credit, Handstand, Burst Oral Care, and PLOWZ & MOWZ.