The Tennis Channel Open was a tennis tournament on the ATP International Series which was held for the first time in Las Vegas, Nevada from February 27 to March 5, 2006. In the men's singles final, James Blake defeated Lleyton Hewitt 7–5, 2–6, 6–3. The men's doubles title was won by Bob and Mike Bryan.
The tournament has been in existence since 1986 located at the Scottsdale Radisson Resort. From 1987–2005 the tournament took place at the Fairmont Scottsdale Princess, where Andre Agassi was crowned champion four times.