Andrea Kay "Missi" Pyle (born November 16, 1972) is an American actress and singer. She has appeared in several films, including the Academy Award-winning film The Artist, Galaxy Quest, Dodgeball: A True Underdog Story, Big Fish, 50 First Dates, Charlie and the Chocolate Factory, Harold & Kumar Escape from Guantanamo Bay and Gone Girl.

She has also appeared in various television roles, on shows such as Mad About You, Friends, Heroes, Two and a Half Men, Frasier, My Name Is Earl, 2 Broke Girls, and Jennifer Falls. She is also half of Smith & Pyle, a desert country-rock band, with actress Shawnee Smith.

Early life

Pyle, the youngest daughter of Linda and Frank Pyle, was born in Houston, Texas, and raised in Memphis, Tennessee. She has two older sisters, Debbie and Julie, two older brothers, Sam and Paul, one younger half-brother, Gordon, and a half-sister, Meredith. Pyle attended the North Carolina School of the Arts in Winston-Salem, North Carolina and graduated in 1995. For her achievements, Pyle was honored by the Poplar Pike Playhouse at her alma mater Germantown High School in Germantown, Tennessee.


Pyle has guest starred on many television shows, including Heroes, Mad About You, Boston Legal, Frasier, The Sarah Silverman Program, and 2 Broke Girls. She started her film career with a minor role in As Good as It Gets, starring Helen Hunt and Jack Nicholson. After her breakout role in Galaxy Quest, she had supporting roles in Bringing Down the House (for which she and Queen Latifah were nominated for an MTV Movie Award for Best Fight), Josie and the Pussycats, Home Alone 4, Exposed, Big Fish, Along Came Polly, Soul Plane, Stormbreaker, and Charlie and the Chocolate Factory. She was also the female lead in BachelorMan. Barely recognizable, she appears in Dodgeball: A True Underdog Story. She also had a brief appearance in 50 First Dates.

Pyle played Jake's Elementary School teacher Ms. Pasternak on Two and a Half Men. The role was recast in 2009 for undisclosed reasons, but Pyle returned to the series in the same role in 2011 and again in the series finale "Of Course He's Dead" in 2015.

In 2008, Missi starred in the Broadway play Boeing-Boeing opposite Christine Baranski, Mark Rylance, Greg Germann, Paige Davis and Rebecca Gayheart. The play closed in January 2009.

Pyle was scheduled to ring the closing bell for the trading day at the New York Stock Exchange on September 29, 2008 to promote Boeing-Boeing, but backed out minutes before the close of trading in order to not associate herself with ending a calamitous day of financial turmoil which resulted in the Dow Jones Industrial Average losing 778 points, the largest point loss ever in a session in the wake of the global financial crisis of September–October 2008. She watched from the floor as an NYSE staffer pushed the button and gaveled the end of trading instead.

She was part of a country music group with actress Shawnee Smith called Smith & Pyle. The two actresses met while filming an ABC comedy pilot titled Traveling in Packs. The band started after Smith invited Pyle to join her in attending the Coachella Valley Music and Arts Festival. While stuck in traffic, Pyle talked about her dream to be a rock star and Smith agreed to form a band with her. Their first album, "It's OK to Be Happy", was released digitally through iTunes and in July 2008. The debut album was recorded in Joshua Tree, California at Rancho de la Luna and was produced by Chris Goss. The two actresses have also become business partners and formed their own record label called Urban Prairie Records, under which "It's OK to be Happy" was released. According to an interview Smith did with in August 2008, a Smith & Pyle television or webisode series might be in the works. Smith also mentioned the idea of a series on Fangoria radio with Dee Snider. Currently there are 3 videos posted on YouTube that show the making of the record. They also have a 10-minute "making of" video on Vimeo called Smith & Pyle: Desert Sessions.

Personal life

Pyle married naturalist Casey Anderson on September 12, 2008. The wedding was country-western themed and took place in Montana. Wedding guests included bandmate Shawnee Smith and comedian Steve Agee. Anderson's pet grizzly bear, Brutus, served as his best man in the ceremony. Pyle and Anderson appeared in "Grizzly Dogs", the October 22, 2010 episode of Dog Whisperer, in which they sought the help of Cesar Millan to rehabilitate their dog. They are no longer together.

Pyle "married" actress and bandmate Shawnee Smith in a faux ceremony at the All Love is Equal Launch Party in West Hollywood on November 18, 2009. The two actresses pretended to get married in support of repealing Prop 8 in California. Actor Hal Sparks dressed as a priest and performed the ceremony with them using rainbow-colored hula hoops as rings.

The drag queen "Pissi Myles" is named after her.



1997As Good as It GetsCafe 24 waitress
1998Number OneLaurelShort film
1999TrickActress with flowers
1999Galaxy QuestLaliari
2000But Enough About Me...Catherine GreyShort film
2001Josie and the PussycatsAlexandra Cabot
2001Let It SnowIly
2003Bringing Down the HouseAshley
2003Big FishMildred
2004Along Came PollyRoxanne
200450 First DatesNoreenUncredited
2004Soul PlaneBarbara Hunkee
2004DodgeBall: A True Underdog StoryFran Stalinovskovichdavidovitchsky
2004Anchorman: The Legend of Ron BurgundyZoo keeperUncredited
2005Civilization of Maxwell Bright, TheThe Civilization of Maxwell BrightCop
2005Charlie and the Chocolate FactoryMrs. Beauregarde
2006Just My LuckPeggy Brayden
2006Mojave Phone BoothSarah
2006StormbreakerNadia Vole
2007Entry LevelLiz
2007Feast of LoveAgatha Smith
2008Meet MarketEricka
2008Pretty Ugly PeopleLucy
2008Harold & Kumar Escape from Guantanamo BayRaylene
2008American CrudeGigi
2008Soccer MomWendy Handler/Coach Lorenzo
2009Spring BreakdownCharlene
2009Still Waiting...Rocky Rhoades/Exotic dancerDirect-to-DVD
2009Taking ChancesFaith Fishback
2009Fork in the Road, AA Fork in the RoadNola
2010Barry MundayLida Griggs
2010Miss NobodyCharmaine
2011Artist, TheThe ArtistConstanceNominated – Broadcast Film Critics Association Award for Best Cast
2011Cinderella Story: Once Upon a Song, AA Cinderella Story: Once Upon a SongGail Van RavenswayDirect-to-DVD
2012My Uncle RafaelBlair Schumacher
2013Percy Jackson: Sea of MonstersGray Sister #3
2013Bakersfield, EarthJudyShort film
2013#RipLydia WaltersShort film
2014Haunted House 2, AA Haunted House 2Noreen
2014Just Before I GoOfficer CT
2014DragulaMaggieShort film
2014Gone GirlEllen Abbott
2014Kiss MePam
2015Uncle NickMichelle
2016Captain FantasticEllen
2016MilesLeslie Wayne
2016Dream BoyMother (voice)Short film
2016Internet FamousKaren Raye Quivers
2016Emma's ChanceSusan Peirce


1999Mad About YouBeautiful womanEpisode: "The Final Frontier: Part 2"
1999Drew Carey Show, TheThe Drew Carey ShowStaceyEpisode: "Drew's Reunion"
1999FriendsHillaryEpisode: "The One with Ross's Teeth"
2000Battery ParkSuzanneEpisode: "Walter's Rib"
2001Ally McBealMarcia HooperEpisode: "Reach Out and Touch"
2001Wayne Brady Show, TheThe Wayne Brady ShowVarious6 episodes
2001RoswellWindy SommersEpisode: "Control"
2001Tick, TheThe TickStacy WaxmanEpisode: "Arthur Needs Space"
2002PhillyCharise DuPreeEpisode: "Mojo Rising"
2002Home Alone 4Vera MerchantsTelevision film
2003FrasierShannon PalmerEpisode: "Maris Returns"
2004–15Two and a Half MenDolores Pasternak3 episodes
2005My Name Is EarlShelly StokerEpisode: "Broke Joy's Fancy Figurine"
2006, 2008Boston LegalRenee Winger3 episodes
2007–10Sarah Silverman Program, TheThe Sarah Silverman ProgramScarlett Lacey4 episodes
2007HeroesHopeEpisodes: "Run!"
2007Wedding Bells, TheThe Wedding BellsAmanda PontellMain cast; 5 episodes
2008American Dad!Tracy, drunk girl, sorority girlVoice; episode: "Spring Breakup"
2008In Plain SightTeri Ranzino/Treena MorrisEpisode: "Never the Bride"
2008Pushing DaisiesBetty BeeEpisode: "Bzzzzzzzzz!"
2009NumbersJanet GalvinEpisode: "Ultimatum"
2010Grey's AnatomyDr. BaylowEpisode: "The Time Warp"
2010Rizzoli & IslesMerch ownerEpisode: "I Kissed a Girl"
2010–11Mentalist, TheThe MentalistKaren Cross2 episodes
2010–11$h*! My Dad SaysKatie Palmer2 episodes
2011American Dad!N/AVoice; episode: "Fart-Break Hotel"
2011Up All NightKayeEpisode: "Mr. Bob's Toddler Kaleidoscope"
2011Family GuyKitty Hawk womanVoice; episode: "Amish Guy"
2012Don't Trust the B---- in Apartment 23Angie BeckencortEpisode: "Whatever It Takes..."
2013NewsreadersRebecca LionwekEpisode: "Auto Erotic"
20131600 PennAgent Sarah HarlanEpisode: "Frosting/Nixon"
20132 Broke GirlsCharity ChanningEpisode: "And Not-So-Sweet Charity"
2013Warehouse 13Lily AbbottEpisode: "The Big Snag"
2013–14Inside Amy SchumerVarious roles3 episodes
2013–14Exes, TheThe ExesSabrina/Julie2 episodes
2013Mindy Project, TheThe Mindy ProjectNancyEpisode: "Mindy Lahiri Is a Racist"
2014Crazy Ones, TheThe Crazy OnesMeloraEpisode: "Dead and Improved"
2014Jennifer FallsDina SimacMain cast (10 episodes)
2015Hot in ClevelandCanadian JoyEpisode: "About a Joy"
2015Law & Order: Special Victims UnitTrudy MalcoEpisode: "Granting Immunity"
2015Z NationBernadetteEpisode: "Rozwell"
2016BordertownGert BuckwaldVoice; main role (13 episodes)
2016The Soul ManAlicia11 episodes
2016Sing It!MarcyMain role
2016Lady DynamiteCarol SimplesEpisode: "A Vaginismus Miracle"


2012Greetings from HomeSue12 episodes
2013–14CleanersEileenMain role (18 episodes)


1996900 OneontaBurning JewelCircle Repertory Theatre
September 15–22, 1996
2008Boeing-BoeingGretchenLongacre Theatre
September 9 – October 7, 2008
2012–13BareSister JoanNew World Stages
December 19, 2012 – February 3, 2013