Jacob William Brendel (born September 10, 1992) is an American football center for the Miami Dolphins of the National Football League (NFL). He played college football at UCLA. Brendel was signed by the Dallas Cowboys as an undrafted free agent in 2016.
A native of Plano, Texas, Brendel attended Plano East Senior High School, where he played on the offensive line his junior and senior seasons and served as team captain, after playing defensive line as a freshman and sophomore. Regarded as a three-star recruit by Rivals.com, Brendel was listed as the No. 15 center prospect in his class. 
After redshirting his initial year at UCLA, Brendel became a fixture at center after spring practice and started all 14 games for the Bruins in 2012.  He was named first-team Freshman All-America by The Sporting News , CBSSports.com, and Football Writers Association of America,    and second-team Freshman All-America by College Football News .  As a junior in 2014, he was team's most experienced offensive lineman. After missing the season opener against Virginia with a knee injury, he returned to start the rest of the season.  Brendel was named to the All-Pac-12 second team.  He requested an evaluation of his NFL draft stock, but decided to return for his senior year,  when he again earned second-team All-Pac-12 honors.  The three-time team captain finished his UCLA career with a school record of 52 starts.  Brendel graduated from UCLA in Spring 2015 with a degree in Business Economics. He was named to the first-team All-Pac 12 Academic team.
After going undrafted in the 2016 NFL Draft, Brendel signed with the Dallas Cowboys on May 6, 2016.  On September 3, 2016, he was released by the Cowboys.  The next day, he was signed to the Cowboys' practice squad.  He was released from the practice squad with an injury settlement.