Husayn Fakhri al-Khalidi (Arabic: حسين فخري الخالدي, Ḥusayn Fakhri al-Khalidī, 1895 – 26 December 1966) was born in Jerusalem. He worked as medical doctor for the Department of Public Health in Aleppo. Khalidi was mayor of Jerusalem from 1934 to 1937, succeeding Raghib al-Nashashibi.
On 1 October 1937, following disturbances and violence during the 1936–39 Arab revolt in Palestine, the British Mandate administration outlawed the AHC and several Arab political parties and arrested a number of Arab political leaders. The Reform Party was dissolved and Khalidi was one of the leaders arrested. He was removed as mayor of Jerusalem and deported to the Seychelles, together with four other Arab nationalist political leaders. He was released in December 1938 to enable him to take part in the London Conference in February 1939, and was among those rejecting the British Government's White Paper of 1939.
He returned to Palestine in 1943 and joined the reformed Arab Higher Committee in 1945, becoming its secretary in 1946. Khalidi was a member of the short-lived All-Palestine Government established under Egypt's patronage in Gaza in September 1948. He published a book of his memoirs in the same year, while exiled in Beirut. He prospered under Jordanian rule, he was custodian and supervisor of the Haram al-Sharif in 1951, became a cabinet minister (for Foreign Affairs) and briefly prime minister in 1957. In 1958, he wrote a book in English entitled Arab Exodus, though it has never been published.
He died on 26 December 1966.