3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.[2][5] It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring.[2][5] EDMA was first synthesised by Alexander Shulgin.[2] In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours.[2] According to Shulgin, EDMA produces a bare threshold consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no additional effects.[2] Scientific research has demonstrated that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release.[5] Based on Shulgin's reports of essential inactivity at 150–250 mg, it might be more active at higher doses.